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KMID : 0614720130560040279
Journal of Korean Medical Association
2013 Volume.56 No. 4 p.279 ~ p.284
Pharmacokinetics and pharmacodynamics of drugs for sedation
Lee Yoon-Sook

Abstract
Pharmacokinetics describes the processes of absorption, distribution, and elimination of drugs and pharmacodynamics describes the effect of drugs on the body. Sedation can be performed by various classes of drugs each with its own mechanism of action and using varying routes of administration: oral, rectal, or parenteral. The course of sedation over time is a reflection of the relationship between pharmacokinetics and pharmacodynamics. The safety and efficacy of sedation is mainly dependant on understanding pharmacologic principles. This review will focus on the general concepts of the pharmacokinetics and pharmacodynamics of drugs used for sedation.
KEYWORD
Pharmacodynamics, Pharmacokinetics, Sedation
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